Arithmetic · real student question

A patient needs 180 micrograms of a drug supplied at a concentration of 2.0 milligrams per 5 cc. What volume in millilitres should be administered?

Question

What volume, in millilitres, should be administered by intramuscular injection to a patient who needs 180180 micrograms of a drug with a concentration of 2.02.0 milligrams per 55 cc?

Step-by-step solution

  1. Fix the units before doing any arithmetic. The dose is in micrograms but the concentration is in milligrams. Convert to a single unit:

    180 μg=180×103 mg=0.18 mg180\ \mu\text{g} = 180 \times 10^{-3}\ \text{mg} = 0.18\ \text{mg}

  2. Note that cc and mL are the same thing. 1 cc=1 mL1\ \text{cc} = 1\ \text{mL} exactly, so the concentration is 2.0 mg2.0\ \text{mg} per 5 mL5\ \text{mL}.

  3. Set up the conversion as a chain of fractions. Dimensional analysis makes the cancellation explicit:

    0.18 mg×5 mL2.0 mg0.18\ \text{mg} \times \frac{5\ \text{mL}}{2.0\ \text{mg}}

    The mg units cancel, leaving mL — which confirms the fraction is the right way up.

  4. Evaluate.

    0.18×52.0=0.92.0=0.45 mL\frac{0.18 \times 5}{2.0} = \frac{0.9}{2.0} = 0.45\ \text{mL}

  5. Check the magnitude. 0.180.18 mg is under a tenth of the 2.02.0 mg in a full 55 mL dose, so the answer should be well under 55 mL. 0.450.45 mL fits.

Answer

0.45 mL0.45\ \text{mL}

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